MIV Therapeutics' Intellectual Property Portfolio Expands to 43 Patents, Patent Applications and Licenses on Novel Technologies Monday September 26, 4:01 pm ET
Aggressive IP Protection of Coating Technologies Positions Company for Entry into $100 Billion Drug-Delivery Market
VANCOUVER, British Columbia--(BUSINESS WIRE)--Sept. 26, 2005--MIV
Therapeutics, Inc. (OTCBB:MIVT - News; Frankfurt/FSE:MIV), a developer of
next-generation biocompatible passive and drug-eluting stent coatings
and drug delivery technologies for the treatment of cardiovascular
disease, has announced that its intellectual property portfolio has
achieved a total of 43 U.S. and international patents and patent
applications. Aggressive steps taken to secure patent protection for
the IP portfolio reflect the Company's vision and business strategy to
generate significant revenues from its proprietary coating solutions,
targeting the projected $100 billion dollar global marketplace for
coronary stents and advanced drug-delivery systems.
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The Company's intellectual property portfolio includes patents
held by the University of British Columbia (UBC) to which MIVT has
exclusive commercial rights under a strategic alliance with the
university. The latest count includes several key patent applications
filed simultaneously in various countries around the world, further
protecting commercial exclusivity of MIVT's inventions in the global
marketplace. The patents from UBC involve MIVT's initial strategic
thrust to commercialize a family of next-generation biocompatible
coatings for stents and other medical devices based on a highly
biocompatible material called Hydroxyapatite (HAp), which has been
shown to be suitable for a broad array of applications as a coating
for coronary stents and next-generation drug-elution/drug-delivery
systems.
"The vigorous expansion and the aggressive protection of
intellectual property portfolio is a central element of MIVT's
high-growth business strategy. Continued growth of our family of
patents, licenses and patent applications reflects methodical pursuit
of important milestones of our corporate progress," said Alan Lindsay,
Chairman and CEO of MIVT. "Our HAp-based coatings and composite drug
delivery technologies have a number of potential broad applications in
cardiovascular and non-vascular drug/device combination products. Our
goal is to continue to develop innovative solutions needed in our
target markets and to diversify our portfolio of solutions to
capitalize on applications that can access the $100 billion market of
combination implantable drug delivery systems."
Mr. Lindsay added, "The market for drug-eluting stents is one of
the fastest growing segments within the medical device arena, with
annual growth approaching 25%, and there is a critical need for
next-generation technologies and solutions to enhance the performance
and safety of devices, while providing competitive advantages to
medical device manufacturers."
In addition to its advanced research and development programs, the
Company is also expanding its intellectual property portfolio through
acquisitions. Earlier this year, MIVT grew its IP portfolio through
acquisition of SagaX, a company developing a range of proprietary
solutions to prevent naturally occurring cardio-embolic strokes and
strokes and other common and serious complications that can result
from cardiac procedures. These technologies include an innovative
proprietary Aortic Embolic Protection Device (AEPD),designed to be
implanted in the aorta during cardiology surgery and procedures, to
filter and/or deflect embolic particles that can cause seriously
debilitating or fatal strokes if left in blood circulation. The unique
AEPD technology being developed at MIVT's SagaX subsidiary is one of
the latest innovations in the field of filter-based embolic protection
devices. It is the only filter being developed for use in the aorta.
SagaX is also developing other proprietary embolic protection
technologies.
The global market for carotid stents and embolic filters, which
are frequently implanted in combination with each other for stroke
prevention purposes, is growing around the world. Currently, the
global market for these devices is estimated at $130 million, but
analysts forecast that such devices will grow into a $500 million to
$1 billion segment of the stent market, according to published
reports.
About MIV Therapeutics, Inc.
MIV Therapeutics, Inc. is developing a next-generation line of
advanced biocompatible coatings for passive and drug-eluting
application on cardiovascular stents and for application on other
implantable medical devices. The Company's unique ultra-thin coatings,
as well as its drug-eluting coatings, are based on a ceramic material
called hydroxyapatite (HAp), a bioactive porous material that makes up
the bone mineral and matrix of teeth and is widely used as a bone
substitute material and for coating implantable fixation devices in
orthopedic, dental and other applications. During in-vivo animal
trials HAp has demonstrated exceptional biocompatibility and excellent
safety pursued by the science in the field of advanced implantable
drug delivery systems. The Company's ultra-thin coating formulation is
designed primarily to protect surrounding tissue from the chemical
interaction with metal stents. The Company's novel drug eluting
technologies are designed to provide an advanced alternative solution
to polymer-based drug eluting coatings currently in the stent market.
The Company's composite drug eluting coating technologies are designed
to suit a broad range of implantable medical devices which may benefit
from a highly customizable drug release profile. MIVT reached a
Collaborative Research Agreement (CRA) with the University of British
Columbia and supported a research and development grant from the
Natural Sciences and Engineering Research Council of Canada (NSERC) in
2002 for the development of Hydroxyapatite as a drug-eluting coating.
In December 2004 MIVT received a Government grant for the research
program titled "Development of Novel Drug Eluting Composite Coatings
for Cardiovascular Stents". For more information, please visit:
http://www.trilogy-capital.com/tcp/mivt/website.html. To read or
download MIV Therapeutics' Investor Fact Sheet, visit
http://www.trilogy-capital.com/tcp/mivt/factsheet.html. To obtain
daily and historical Company stock quote data, and recent Company news
releases, visit http://www.trilogy-capital.com/tcp/html/mivt.htm. MIVT
is also traded on the Frankfurt Stock Exchange under the ticker symbol
MIV.
Forward-Looking Statements
Except for the historical information contained herein, the
matters discussed in this press release are forward-looking
statements. Such statements are indicated by words or phrases such as
"believe," "will," "breakthrough," "significant," "indicated," "feel,"
"revolutionary," "should," "ideal," "extremely" and "excited." These
statements are made under "Safe Harbor" provisions of the Private
Securities Litigation Reform Act of 1995. Actual results may differ
materially from those described in forward-looking statements and are
subject to risks and uncertainties. See the Company's filings with the
Securities and Exchange Commission including, without limitation, the
Company's recent Form 10-K and Form 10-Qs, which identify specific
factors that may cause actual results or events to differ materially
from those described in the forward-looking statements.
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